Synthesis and Characterization of Heterocyclic Compounds with Neuroprotective Properties for Neurodegenerative Disease Treatment

Neurodegenerative illnesses are progressive and have few available treatments, they pose serious global health issues. Examples of these diseases are Alzheimer's, Parkinson's, and Huntington's. This work synthesizes and characterizes new heterocyclic compounds with neuroprotective characteristics in order to solve these problems. These compounds were produced by a sequence of chemical processes and examined using sophisticated spectroscopic methods like mass spectrometry, IR, and NMR. They are well-known for their structural diversity and biological activity. Their capacity to prevent neuronal cell death, lessen oxidative stress, and alter important signaling pathways involved in neurodegeneration was demonstrated during tests of their neuroprotective efficacy both in vitro and in vivo. According to preliminary findings, a number of these substances have notable neuroprotective properties, highlighting their potential as therapeutic possibilities. Through important insights into the design and development of therapeutic medicines targeting the causes of neuronal damage and dysfunction, this research contributes to the hunt for effective treatments for neurodegenerative diseases.

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Publication Details

Published
2025-05-01
DOI
https://doi.org/10.38124/ijisrt/25apr1824
Primary Topic
Cholinesterase and Neurodegenerative Diseases
Type
article
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article

Synthesis and Characterization of Heterocyclic Compounds with Neuroprotective Properties for Neurodegenerative Disease Treatment

Pushpendra Tiwari, Chavan Akshay Sukhadev
Cholinesterase and Neurodegenerative Diseases
article

Synthesis and Characterization of Heterocyclic Compounds with Neuroprotective Properties for Neurodegenerative Disease Treatment

Pushpendra Tiwari, Chavan Akshay Sukhadev
article en

Abstract

Neurodegenerative illnesses are progressive and have few available treatments, they pose serious global health issues. Examples of these diseases are Alzheimer's, Parkinson's, and Huntington's. This work synthesizes and characterizes new heterocyclic compounds with neuroprotective characteristics in order to solve these problems. These compounds were produced by a sequence of chemical processes and examined using sophisticated spectroscopic methods like mass spectrometry, IR, and NMR. They are well-known for their structural diversity and biological activity. Their capacity to prevent neuronal cell death, lessen oxidative stress, and alter important signaling pathways involved in neurodegeneration was demonstrated during tests of their neuroprotective efficacy both in vitro and in vivo. According to preliminary findings, a number of these substances have notable neuroprotective properties, highlighting their potential as therapeutic possibilities. Through important insights into the design and development of therapeutic medicines targeting the causes of neuronal damage and dysfunction, this research contributes to the hunt for effective treatments for neurodegenerative diseases.

Openalex Percentile: Top 89%
Cholinesterase and Neurodegenerative Diseases
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Synthesis and Characterization of Heterocyclic Compounds with Neuroprotective Properties for Neurodegenerative Disease Treatment — Pushpendra Tiwari, Chavan Akshay Sukhadev · (2025) | TGRS Research Map | TGRS