The Clinical Value of NeuroQuant Hippocampal Volumes and Hippocampal Occupancy Scores in an Academic Medical Center Memory Clinic
NeuroQuant HVs and HOCs were lower in participants with amnestic MCI, AD, and memory impairment, but had poor sensitivity and specificity to predict memory impairment, and only a modest association with measurable memory impairment. These measures should be used cautiously as supporting diagnostic tools.
Authors
- Jeff Schaffert (ORCID: https://orcid.org/0000-0002-8842-980X)
- Robert Ruchinskas (ORCID: https://orcid.org/0000-0001-9243-9341)
- Alka Khera (ORCID: https://orcid.org/0000-0002-8584-3909)
- Trung Nguyen (ORCID: https://orcid.org/0000-0002-6339-6159)
- William Goette (ORCID: https://orcid.org/0000-0003-2909-1068)
Institutions
- Allen Institute for Brain Science (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Cognitive and Behavioral Neurology
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1097/wnn.0000000000000390
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00