For girls and women (4GW) HPV RCT protocol: a crowdsourced, pragmatic stepped-wedge cluster randomized trial to improve uptake of HPV vaccination and screening among mother-daughter dyads in Nigeria
This study is a unique dyadic intervention focused on both girls and their mothers or female caregivers to drive cervical cancer control in Africa. Findings have the potential to inform local and global policies aimed at reducing the cervical cancer burden in African countries like Nigeria, eliminating missed opportunities by closing the research-to-translation gap. The protocol was registered with clinicaltrials.gov under registration NCT06728085.
Authors
- Benedict Ndubueze Azuogu (ORCID: https://orcid.org/0000-0002-0108-4029)
- Assanatou Bamogo (ORCID: https://orcid.org/0000-0003-3063-6504)
- Jason J. Ong (ORCID: https://orcid.org/0000-0001-5784-7403)
- Kayode Olusegun Ajenifuja (ORCID: https://orcid.org/0000-0001-9823-5892)
- Oliver Ezechi (ORCID: https://orcid.org/0000-0003-0688-3898)
- Zhuoru Zou (ORCID: https://orcid.org/0000-0001-8837-0900)
- Folahanmi Tomiwa Akinsolu (ORCID: https://orcid.org/0000-0002-6782-9820)
- Abdulhammed Babatunde
- Ucheoma Nwaozuru (ORCID: https://orcid.org/0000-0002-0680-0928)
- Agatha Wapmuk (ORCID: https://orcid.org/0009-0001-6040-0474)
- Mengmeng Jia (ORCID: https://orcid.org/0000-0002-8175-7181)
- Jennifer S. Smith (ORCID: https://orcid.org/0000-0002-1256-0422)
- Juliet Iwelunmor (ORCID: https://orcid.org/0000-0003-1376-5443)
- Lei Zhang (ORCID: https://orcid.org/0000-0002-3007-7194)
- Hong Xian (ORCID: https://orcid.org/0000-0002-7549-4880)
- Temitope Ojo (ORCID: https://orcid.org/0000-0002-3581-259X)
- Titilola Gbaja‐Biamila (ORCID: https://orcid.org/0000-0003-2958-2924)
- Joseph D. Tucker (ORCID: https://orcid.org/0000-0003-2804-1181)
- Olufunto Olusanya
- Ekenechukwu Kokelu
- Collins O. Airhihenbuwa (ORCID: https://orcid.org/0000-0001-5789-1551)
- Adesola Z. Musa (ORCID: https://orcid.org/0009-0006-6331-0040)
- Peter Kalulu (ORCID: https://orcid.org/0009-0003-6023-962X)
- Angel Obiorah
- Maria Afadapa (ORCID: https://orcid.org/0000-0002-1547-989X)
- Nkiruka Obodoechina
- Onyeka Anikamadu
Institutions
- Northwestern University (US)
- University of North Carolina at Chapel Hill (US)
- Georgia State University (US)
- University of Ibadan (NG)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Washington University in St. Louis (US)
- London School of Hygiene & Tropical Medicine (GB)
- Melbourne Sexual Health Centre (AU)
- Alfred Health (AU)
- Obafemi Awolowo University (NG)
- Wake Forest University (US)
- Saint Louis University (US)
- Nigerian Institute of Medical Research (NG)
- Monash University (AU)
- Lead City University (NG)
- Nanjing Medical University (CN)
- Xi'an Jiaotong University (CN)
- Ebonyi State University (NG)
Publication Details
- Journal
- Implementation Science
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1186/s13012-025-01428-5
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Cancer Institute