Challenges and insights in detecting early inflammation in DSS-induced colitis using chemiluminescence
This study demonstrates the progression of inflammation in acute and chronic colitis models. However, in vivo chemiluminescence imaging did not reliably detect the onset of inflammation, limiting its application for early-stage disease detection. Ex vivo chemiluminescence and FOB tests provided more consistent insights into inflammation dynamics, addressing the need for improved non-invasive monitoring tools in UC research.
Authors
- Paulína Belvončíková (ORCID: https://orcid.org/0000-0003-2375-9696)
- Barbora Konečná (ORCID: https://orcid.org/0000-0002-5544-1482)
- Barbora Gromová (ORCID: https://orcid.org/0000-0001-9613-0237)
- Roman Gardlík (ORCID: https://orcid.org/0000-0001-8211-907X)
Institutions
- Comenius University Bratislava (SK)
Publication Details
- Journal
- Photochemical & Photobiological Sciences
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1007/s43630-025-00724-9
- Primary Topic
- Medical and Biological Ozone Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Univerzita Komenského v Bratislave
- Ministerstvo školstva, vedy, výskumu a športu Slovenskej republiky
- Agentúra na Podporu Výskumu a Vývoja
- Vedecká Grantová Agentúra MŠVVaŠ SR a SAV