Mechanosensitive Channels Mediate Pancreatic β Cells Reactive Oxygen Species Formation and Downregulation of Essential Genes During Therapeutic Ultrasound Treatment
We report the expression of TRPV2, TRPV5, and piezo1 in human and rodent pancreatic β cells that are implicated in both TUS-mediated ROS formation and the downregulation of essential β cell genes.
Authors
- Vesna Zderic (ORCID: https://orcid.org/0000-0001-7572-3922)
- Aleksandar Jeremić (ORCID: https://orcid.org/0000-0002-9350-0121)
- Mallory Brayer (ORCID: https://orcid.org/0009-0002-0133-0784)
Institutions
- George Washington University (US)
Publication Details
- Journal
- Journal of Ultrasound in Medicine
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1002/jum.16712
- Citations
- 1
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- National Institutes of Health