Oscillation between Hyperthyroidism and Hypothyroidism in an Adolescent Female with Graves' Disease

Graves' disease (GD) presenting as fluctuations between hyperthyroidism and hypothyroidism is a rare phenomenon and poses a diagnostic challenge. A 14-year-old female with GD, initially thought to have Hashimoto's thyroiditis presented with a goiter and oscillating thyroid function over the course of 4 years. This case depicts a case of GD with oscillating thyroid function and stresses the importance of TSH receptor antibodies (TRAb) in the evaluation of patients with hyperthyroidism without Graves' ophthalmopathy.