RGS14 promotes the progression of hepatocellular carcinoma by activating the cAMP/PKA/CREB signaling pathway
Our findings suggest that RGS14 plays a critical oncogenic role in HCC by regulating cAMP/PKA/CREB pathway activation, underscoring its potential as both a prognostic marker and therapeutic target for HCC patients.
Authors
- Bin Xu (ORCID: https://orcid.org/0000-0001-7998-9314)
- Xiangnan Liang
- Kexin Ma (ORCID: https://orcid.org/0009-0005-7864-0416)
- Kai Gong (ORCID: https://orcid.org/0000-0002-2903-5341)
- Binwen Sun (ORCID: https://orcid.org/0000-0001-5360-4439)
- Liming Wang (ORCID: https://orcid.org/0000-0002-7256-8776)
- Chun Han (ORCID: https://orcid.org/0000-0003-4925-0388)
- Qiuxiang Wang (ORCID: https://orcid.org/0000-0002-6316-8279)
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Journal of Cancer Research and Clinical Oncology
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1007/s00432-025-06212-y
- Citations
- 3
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 3.14
Funders
- National Natural Science Foundation of China