Inhibition of CD45-specific phosphatase activity restores the differentiation potential of aged mesenchymal stromal cells: implications in regenerative medicine
CD45 can be used as an aging marker for mesenchymal stem cells. Alteration of CD45 phosphatase activity could have significant implications for the use of MSCs in regenerative medicine.
Authors
- Madhurima Das (ORCID: https://orcid.org/0000-0001-7515-3632)
- Isha Behere (ORCID: https://orcid.org/0000-0002-9737-2454)
- Ganesh Ingavle (ORCID: https://orcid.org/0000-0001-5044-2075)
- Vaijayanti Kale (ORCID: https://orcid.org/0000-0001-7498-7563)
- Anuradha Vaidya (ORCID: https://orcid.org/0000-0001-7451-7414)
Institutions
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Symbiosis International University (IN)
Publication Details
- Journal
- Biological Research
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1186/s40659-025-00603-8
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Biotechnology, Ministry of Science and Technology, India