Nerve Types and Classification of Neurons Innervating Oral Cancer
This study is the first comprehensive characterization of nerve types in OSCC with classification of innervating trigeminal sensory neurons. Our findings emphasize the importance of sensory innervation in OSCC and are highly relevant for mechanistic and translational studies on treatment strategies.
Authors
- Peng Li (ORCID: https://orcid.org/0000-0002-8992-0350)
- Cindy Perez‐Pacheco (ORCID: https://orcid.org/0000-0002-7642-7639)
- Nisha J. D’Silva (ORCID: https://orcid.org/0000-0001-7030-3187)
- Laura Gonzalez-Maldonado (ORCID: https://orcid.org/0000-0002-0964-916X)
- Noam Gannot
- Allison Furgal (ORCID: https://orcid.org/0000-0001-8081-2444)
- Joshua J. Emrick (ORCID: https://orcid.org/0000-0001-5619-1078)
- Ligia B. Schmitd (ORCID: https://orcid.org/0000-0003-1570-6543)
- Gregory T. Wolf (ORCID: https://orcid.org/0000-0002-3219-9515)
- Laura S. Rozek (ORCID: https://orcid.org/0000-0001-6731-7000)
- Yihan Li (ORCID: https://orcid.org/0009-0003-6755-3451)
- Sienna K. Perry (ORCID: https://orcid.org/0000-0003-2964-9842)
- Brian S.C. Constantinescu (ORCID: https://orcid.org/0009-0008-4456-076X)
Institutions
- Georgetown University (US)
- University of Michigan (US)
- Georgetown University Medical Center (US)
- Michigan United (US)
- Michigan Center for Translational Pathology (US)
- Ann Arbor VA Medical Center (US)
- Vince Lombardi Cancer Clinic (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-2375
- Citations
- 3
- Primary Topic
- Cancer, Stress, Anesthesia, and Immune Response
- Type
- article
- Field-Weighted Citation Impact
- 4.41
Funders
- School of Dentistry, University of Michigan
- National Institute of Dental and Craniofacial Research