Complement C3/C3aR Signaling Pathway Inhibition Ameliorates Retinal Damage in Experimental Retinal Vein Occlusion

The complement C3/C3aR signaling pathway is critically involved in RVO-induced retinal damage and targeting this pathway may be a promising approach for RVO treatment.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2025-05-01
DOI
https://doi.org/10.1167/iovs.66.5.2
Citations
3
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
5.12
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article

Complement C3/C3aR Signaling Pathway Inhibition Ameliorates Retinal Damage in Experimental Retinal Vein Occlusion

Heping Xu, Zhengwei Ge, Juan Chen, Zhongping Chen et al.
3 citations
Investigative Ophthalmology & Visual Science
Retinal Diseases and Treatments
5.12
article

Complement C3/C3aR Signaling Pathway Inhibition Ameliorates Retinal Damage in Experimental Retinal Vein Occlusion

Heping Xu, Zhengwei Ge, Juan Chen, Zhongping Chen, Hengwei Liu, Yufan Zhou, Yanying Zhao, Tingting Guo
article en
3 citations

Abstract

The complement C3/C3aR signaling pathway is critically involved in RVO-induced retinal damage and targeting this pathway may be a promising approach for RVO treatment.

Investigative Ophthalmology & Visual ScienceVol. 66(5)
Queen's University Belfast (GB), Central South University (CN), Jinan University (CN), Hubei University of Science and Technology (CN), He Eye Hospital (CN)
Zero hunger
Openalex Percentile: Top 5%
Retinal Diseases and Treatments
5.12
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Complement C3/C3aR Signaling Pathway Inhibition Ameliorates Retinal Damage in Experimental Retinal Vein Occlusion — Heping Xu, Zhengwei Ge, et al. · Investigative Ophthalmology & Visual Science (2025) | TGRS Research Map | TGRS