Modeling Population-Level Impacts of Cell-Free DNA Screening for Colorectal Cancer in Canada
This study suggests that cfDNA testing could result in increased detection of colorectal cancer and reduced mortality if higher participation than reported in previous studies is achieved at the population level. Patient input on acceptance of blood-based vs stool-based screening may help inform real-world implementation.
Authors
- Carl James Brown (ORCID: https://orcid.org/0000-0002-5368-3541)
- Yibing Ruan (ORCID: https://orcid.org/0000-0002-2417-7172)
- Jonathan M. Loree (ORCID: https://orcid.org/0000-0001-8189-2132)
- Brendan J. Chia (ORCID: https://orcid.org/0009-0000-4337-7076)
- Robert J. Hilsden (ORCID: https://orcid.org/0000-0003-1545-1093)
- Darren R. Brenner (ORCID: https://orcid.org/0000-0003-1305-2582)
- John M. Hutchinson (ORCID: https://orcid.org/0000-0003-0937-2882)
Institutions
- Alberta Health Services (CA)
- BC Cancer Agency (CA)
- Providence Health Care (CA)
- University of Calgary (CA)
- St. Paul's Hospital (CA)
Publication Details
- Journal
- JAMA Oncology
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1001/jamaoncol.2025.0908
- Citations
- 1
- Primary Topic
- Colorectal Cancer Screening and Detection
- Type
- article
- Field-Weighted Citation Impact
- 1.05