Dual effects of vaginal Candida albicans on human papillomavirus infection: A large-scale multicenter study in Chinese women
Statement: This study demonstrates for the first time that C. albicans exhibits opposing effects on HPV infection at different stages, suggesting stage-specific host-microbe interactions that may influence viral pathogenesis. These findings have important implications for understanding the role of fungal colonization in viral infections and may inform strategies for HPV management.
Authors
- Rongdan Chen (ORCID: https://orcid.org/0000-0002-1081-4185)
- Cancan Qi (ORCID: https://orcid.org/0000-0003-3825-5802)
- Muxuan Chen (ORCID: https://orcid.org/0000-0002-8961-2649)
- Yan He (ORCID: https://orcid.org/0009-0001-1435-5860)
- Hongwei Zhou (ORCID: https://orcid.org/0000-0002-7518-9464)
- Zuyi Zhou
- Xiaoxin Song (ORCID: https://orcid.org/0000-0003-3259-5101)
- Qing Wei (ORCID: https://orcid.org/0000-0002-8651-3012)
- Yingxuan Zhang (ORCID: https://orcid.org/0000-0001-6403-3838)
- Yating Zou
Institutions
- Zhujiang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.jare.2025.04.049
- Citations
- 3
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 3.55
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- National Key Research and Development Program of China
- Basic and Applied Basic Research Foundation of Guangdong Province