Management of non-Cardiac Organ Failure in cardiogenic shock
Cardiogenic shock (CS) is a syndrome of low cardiac output leading to systemic hypoperfusion. The mainstay of management involves optimizing preload, afterload, and contractility to restore central hemodynamics. However, CS is frequently complicated by non-cardiac organ failure, for which there is limited guidance. Herein, we review the pathophysiology, assessment, and management of respiratory, renal, hepatic, and neurological failure in the context of CS. This review is intended to provide an evidence-based framework for the management of extracardiac sequelae for the patients in the cardiac and medical intensive care unit.
Authors
- Brian Osorio
- Marwan Saad
- Iván Vargas (ORCID: https://orcid.org/0000-0002-0787-5630)
- Sandipan Shringi (ORCID: https://orcid.org/0000-0001-9964-927X)
- Rachna Kataria (ORCID: https://orcid.org/0000-0001-9065-7687)
- Sahas Chandragiri
- Athena Poppas (ORCID: https://orcid.org/0000-0001-9238-1784)
- Mark Godding
- Omar Hyder (ORCID: https://orcid.org/0000-0002-0965-5543)
- Neel R. Sodha (ORCID: https://orcid.org/0000-0001-9720-9895)
- J. Dawn Abbott (ORCID: https://orcid.org/0000-0002-2560-0155)
- Saraschandra Vallabhajosyula (ORCID: https://orcid.org/0000-0002-1631-8238)
- Ali A. Khan (ORCID: https://orcid.org/0009-0007-0058-7453)
- Paola Beatriz Vergara Díaz
- Ergeng Hao
- Nicholas Potter
- Abraham Shin
- Chirag Mehta
- Daniel DePolo
Institutions
- Brown University (US)
Publication Details
- Journal
- American Heart Journal Plus Cardiology Research and Practice
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.ahjo.2025.100549
- Citations
- 1
- Primary Topic
- Cardiac Arrest and Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 2.25