Optimizing performance of electrolyte-gated organic field-effect transistors for biosensing: material variations and parameter analysis

This work thoroughly examines the performance evaluation of electrolyte-gated organic field-effect transistors (EGOFETs) for biosensing applications, focusing on materials and parameter optimization. It analyzes the effects of four organic semiconductor (OSC) materials (P3HT, PBTTT-C16, PEDOT, polyfluorene) and four electrolyte materials (PVDF, PVA, PSSH, PEO) using simulation software. The study finds that the combination of PSSH as the electrolyte and PBTTT-C16 as the OSC exhibits promising performance, with large drain currents, enhanced thermal stability, and a maximum transconductance of 2.25 mS. Key parameters such as electrolyte thickness (6–12 µm), electrolyte concentration (100–10−4 mol/m3), temperature (293–320 K), and OSC hole concentration (10–3–10–7 mol/m3) are optimized. This research lays the groundwork for developing highly sensitive and reliable EGOFET-based biosensing platforms for healthcare and environmental monitoring.