Ce(OTf)<sub>3</sub>-Catalyzed Asymmetric 6π Cyclization of Triaryldivinyl Ketones
The rare-earth Ce(OTf)<sub>3</sub>-catalyzed asymmetric 6π cyclization of triaryldivinyl ketones is realized, affording methyl (<i>R</i>,<i>E</i>)-1-aryl-2-arylmethylidene-3-hydroxy-1,4-dihydronaphthalene-2-carboxylates in moderate to good yields with good to excellent enantioselectivities. The reaction provides a new strategy for the construction of optically active 3-hydroxy-1,4-dihydronaphthalene-2-carboxylic acid derivatives.
Authors
- Wei Hao (ORCID: https://orcid.org/0000-0001-9493-6894)
- Zhanhui Yang (ORCID: https://orcid.org/0000-0001-7050-8780)
- Liu Li (ORCID: https://orcid.org/0000-0001-9339-2530)
- Jiaxi Xu (ORCID: https://orcid.org/0000-0002-9039-4933)
Institutions
- Beijing University of Chemical Technology (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1021/acs.orglett.5c01081
- Citations
- 6
- Primary Topic
- Catalytic Alkyne Reactions
- Type
- article
- Field-Weighted Citation Impact
- 5.62
Funders
- National Key Research and Development Program of China