THE CLINICAL CASE OF COVID-ASSOCIATED MUCORMYCOSIS OF THE CRANIOFACIAL REGION

Background data. A clinical case of mucormycosis of the cranio-maxillofacial region, which occurred as a complication after a new coronavirus infection (COVID-19), against the background of diabetes mellitus and therapy of the underlying disease with glucocorticosteroids (GCS). Subject. COVID-19 is a possible cause of the development of potentially dangerous complications, a special place among which is occupied by mycotic complications, and in particular, mucormycosis of the cranio-maxillofacial region. In the vast majority of cases, this complication was found in patients who underwent COVID-19, were on GCS therapy and had a history of type 2 diabetes mellitus. Objective. To study and describe a case of mucormycosis of the cranio-maxillofacial region, which occurred as a complication after COVID-19 on the background of GCS treatment. Materials and methods. We analyzed the medical records of a patient with mucormycosis of the cranio-maxillofacial region, which occurred as a complication after COVID-19, on the background of hormonal therapy and the presence of diabetes mellitus in the anamnesis. Results. A patient with mucormycosis of the right and left upper jaw, sinuses, zygomatic bone and arch on the left side, developed against the background of COVID-19, was urgently hospitalised in the department of maxillofacial and plastic surgery of the Regional Clinical Hospital No.2 in Tyumen. During his stay in hospital, he received surgical, antimicrobial and intensive medical care. After treatment he was discharged with residual neurological consequences and defects of the middle facial zone structures. Conclusions. 1. The cause of mucormycosis of cranio-maxillofacial region is the decrease of organism resistance against the background of COVID-19 and GCS therapy. 2. Changes of vascular wall characteristic for patients with diabetes mellitus and arterial hypertension also create conditions for lightning angioinvasive spread of mucormycosis.