Comparison of circulating immune signatures across different consensus molecular subtypes (CMS) and between left- and right-sided lesions in stage II colorectal cancer using single-cell mass cytometry
The frequency and phenotype of circulating immune cells are influenced by tumor side and CMS subtypes in stage II CRC. These observations provide a basis for further investigation into the mechanisms linking tumors and systemic immunity.
Authors
- Xiangqian Su (ORCID: https://orcid.org/0000-0002-0667-8141)
- Chuanyong Zhou (ORCID: https://orcid.org/0000-0003-1102-9557)
- Pin Gao (ORCID: https://orcid.org/0000-0002-1712-0944)
- Zaozao Wang (ORCID: https://orcid.org/0000-0001-5599-483X)
- Hong Yang (ORCID: https://orcid.org/0000-0002-2847-668X)
- Beihai Jiang (ORCID: https://orcid.org/0000-0002-3665-9291)
- Jiabo Di (ORCID: https://orcid.org/0000-0003-3665-3911)
- Shunyu Deng
Institutions
- Peking University (CN)
- Peking University Cancer Hospital (CN)
- Ministry of Education (ET)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1186/s12967-025-06481-8
- Citations
- 4
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Beijing Municipality
- Peking University