Multiomic Characterization of <i>RCC1</i> and <i>RCC2</i> Expression and Their Association With Molecular Alterations, Immune Phenotypes, and Cancer Outcomes
<i>RCC1</i> and <i>RCC2</i> expression is a negative prognostic marker in NSCLC, PC, and CRC. Further studies to investigate <i>RCC1</i> and <i>RCC2</i> function at the molecular level may provide opportunities for novel targeted drug development.
Authors
- Ammar Sukari (ORCID: https://orcid.org/0000-0003-1968-0459)
- Sahar F. Bannoura (ORCID: https://orcid.org/0009-0008-1832-902X)
- Dave S.�B. Hoon (ORCID: https://orcid.org/0000-0003-1915-3683)
- Brian Warnecke (ORCID: https://orcid.org/0000-0002-9939-6185)
- Boris Pasche (ORCID: https://orcid.org/0000-0002-3750-7898)
- Mohammed Najeeb Al Hallak (ORCID: https://orcid.org/0000-0002-4598-8177)
- Milan M. Radovich (ORCID: https://orcid.org/0000-0001-9667-156X)
- Misako Nagasaka (ORCID: https://orcid.org/0000-0001-5308-615X)
- Emil Lou (ORCID: https://orcid.org/0000-0002-1607-1386)
- George W. Sledge (ORCID: https://orcid.org/0000-0003-0297-0775)
- Sourat Darabi (ORCID: https://orcid.org/0000-0002-3395-894X)
- Wafik S. El‐Deiry (ORCID: https://orcid.org/0000-0002-9577-8266)
- Balázs Halmos (ORCID: https://orcid.org/0000-0001-7548-8360)
- Sai‐Hong Ignatius Ou (ORCID: https://orcid.org/0000-0002-1764-4975)
- Chul Kim (ORCID: https://orcid.org/0000-0003-0191-8684)
- Andrew Elliott (ORCID: https://orcid.org/0009-0001-9302-8189)
Institutions
- University of Minnesota (US)
- Hoag Memorial Hospital Presbyterian (US)
- Montefiore Medical Center (US)
- St. Marianna University School of Medicine (JP)
- Georgetown University (US)
- Wayne State University (US)
- University of California, Irvine (US)
- Brown University (US)
- The Barbara Ann Karmanos Cancer Institute (US)
- Saint John's Health Center (US)
- Caris Life Sciences (United States) (US)
- St. John's School (US)
Publication Details
- Journal
- JCO oncology advances.
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1200/oa-24-00033
- Primary Topic
- DNA Repair Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00