A pilot study of intraoperative melphalan to prevent recurrent PVR: the IOMPVR study
In this pilot study, the preliminary data showed that PPV followed by intravitreal injection of 5 µg/0.1 ml melphalan was not related to ocular toxicity. The absence of PVR recurrence at 3 months follow-up in these complex PVR eyes is an interesting finding that justifies further investigation.
Authors
- Lucas Zago Ribeiro (ORCID: https://orcid.org/0000-0001-9130-1500)
- Luiz H. Lima (ORCID: https://orcid.org/0000-0001-7304-909X)
- Carlos Augusto Moreira Neto (ORCID: https://orcid.org/0000-0001-7370-6395)
- Michel Eid Farah (ORCID: https://orcid.org/0000-0001-5951-0193)
- José Barbosa (ORCID: https://orcid.org/0000-0002-9929-1703)
- José S. Pulido (ORCID: https://orcid.org/0000-0003-2009-3163)
- Fábio Augusto Nascimento (ORCID: https://orcid.org/0000-0002-7161-6385)
- Maurício Maia (ORCID: https://orcid.org/0000-0002-7034-8091)
- Daniel Lavinsky (ORCID: https://orcid.org/0000-0001-7197-1259)
- Acácio Alves de Souza Lima Filho (ORCID: https://orcid.org/0000-0003-1802-9592)
- Luiz Fernando Teixeira (ORCID: https://orcid.org/0000-0002-5241-0541)
- Talita de Oliveira
- Luca Bongiovanni de Miranda Gonçalves
- Gabriel Nunes de Figueiredo Cavalcanti
- Octaviano Magalhães (ORCID: https://orcid.org/0009-0005-3102-224X)
- Fernando Ejii Ogata
Institutions
- Universidade Estadual do Paraná (BR)
- Support group for adolescents and children with cancer (BR)
- Instituto da Visão (BR)
- He Eye Hospital (CN)
- Wills Eye Hospital (US)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- International Journal of Retina and Vitreous
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1186/s40942-025-00675-4
- Citations
- 1
- Primary Topic
- Retinal and Macular Surgery
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico