Association between serum α-klotho levels and the incidence of diabetic kidney disease and mortality in type 2 diabetes: evidence from a Chinese cohort and the NHANES database
There exists a notable association between α-klotho levels and DKD risk, along with mortality in T2DM patients, with varying effects based on gender. These results highlight the potential importance of α-klotho as both a biomarker and a therapeutic target.
Authors
- Jin Qian (ORCID: https://orcid.org/0000-0002-9368-387X)
- Mengqi Zhou
- Yi Kang (ORCID: https://orcid.org/0000-0002-0166-0823)
- Yaoxian Wang (ORCID: https://orcid.org/0000-0002-1927-9529)
- Huijuan Zheng (ORCID: https://orcid.org/0000-0002-0389-3989)
- Jingwei Zhou (ORCID: https://orcid.org/0000-0002-2377-0409)
- D R Li
- Jie Lv
Institutions
- Beijing University of Chinese Medicine (CN)
- Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine (CN)
- Beijing Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1186/s13098-025-01711-x
- Primary Topic
- Parathyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China