Aplasia Cutis Congenita on the Scalp

Aplasia cutis congenita is a rare condition characterized by localized absent skin at birth, often affecting the scalp. The exact pathogenesis is unclear, but it is likely related to disrupted prenatal skin development. Potential etiologies include genetic factors, trauma, intrauterine infections, teratogens, incomplete neural tube closure, and vascular compromise. We present a case of aplasia cutis congenita on the scalp potentially associated with maternal methimazole use.