High-Content Screening of Wind-Dampness Dispelling Traditional Chinese Medicines against Podocyte EMT Induced by IgA1
By quantifying the changes in the expression of EMT markers during pIgA1- induced EMT, this study successfully identified wind-dampness dispelling TCM extracts with anti-EMT properties using an HCS system. In addition, the proposed approach presents a novel avenue for the identification of wind-dampness-dispelling TCMs for the treatment of pIgA1- induced EMT.
Authors
- Yu Jin (ORCID: https://orcid.org/0000-0001-6607-4609)
- Caifeng Zhu
- Yue Sun (ORCID: https://orcid.org/0000-0003-2478-0980)
- Ling-li Zhu
Institutions
- Zhejiang Chinese Medical University (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
- Jinhua Central Hospital (CN)
Publication Details
- Journal
- Combinatorial Chemistry & High Throughput Screening
- Published
- 2025-04-29
- DOI
- https://doi.org/10.2174/0113862073350741250410053000
- Primary Topic
- Transgenic Plants and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00