Exploring the Efficacy and Mechanism of Astragalus Polysaccharide inTreating Allergic Asthma through Network Pharmacology,Bioinformatics, and Experimental Verification
Our study suggests that APS may treat allergic asthma by targeting the PI3K/AKT signaling pathway. This provides a basis for preliminary research on the clinical application of APS for treating allergic asthma.
Authors
- Yihang Zhang (ORCID: https://orcid.org/0000-0002-5010-9165)
- Linhan Hu (ORCID: https://orcid.org/0000-0003-4895-1203)
- Honglei Zhang (ORCID: https://orcid.org/0000-0002-7781-2520)
- Linpeng Cong
- Qi Wang (ORCID: https://orcid.org/0000-0001-5619-0825)
- Ji Wang (ORCID: https://orcid.org/0009-0003-7659-0158)
- Lei Wang (ORCID: https://orcid.org/0000-0002-4342-8520)
- Yumei Zhou (ORCID: https://orcid.org/0000-0002-1267-5940)
- Haiyun Zhang (ORCID: https://orcid.org/0000-0003-4229-1048)
- Juntong Liu (ORCID: https://orcid.org/0000-0003-1465-4171)
Institutions
- Henan University of Traditional Chinese Medicine (CN)
- Beijing University of Chinese Medicine (CN)
- Hubei University of Chinese Medicine (CN)
- Dalian Maternal and Child Health Hospital (CN)
Publication Details
- Journal
- Combinatorial Chemistry & High Throughput Screening
- Published
- 2025-04-29
- DOI
- https://doi.org/10.2174/0113862073368307250409055727
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00