Standardization challenges in antipsychotic drug monitoring: insights from a national survey in Chinese TDM practices
Urgent standardization of Chinese TDM practices is needed, including harmonized systems and traceable calibrators. While commercial kits enhance result consistency, further efforts are required to harmonize performance across manufacturers. Lyophilized materials are optimal for EQA due to their stability and ease of transport. These findings offer actionable insights to improve the quality and comparability of antipsychotic TDM in clinical practice.
Authors
- Haoyu Deng (ORCID: https://orcid.org/0000-0001-9074-2988)
- Chuanbao Zhang (ORCID: https://orcid.org/0000-0003-0754-7511)
- Jing Wang (ORCID: https://orcid.org/0000-0003-3694-6001)
- Jie Ma (ORCID: https://orcid.org/0000-0002-2938-818X)
- Jiangtao Zhang (ORCID: https://orcid.org/0000-0002-5067-7912)
- Weiyan Zhou (ORCID: https://orcid.org/0000-0003-4174-6047)
- Yuhang Deng (ORCID: https://orcid.org/0000-0003-4910-0267)
- Lidan Zhang (ORCID: https://orcid.org/0000-0003-1347-6211)
- Wenxiang Chen (ORCID: https://orcid.org/0000-0001-5704-3368)
- Qianwen Zhang (ORCID: https://orcid.org/0000-0002-1058-3348)
- Haijian Zhao (ORCID: https://orcid.org/0000-0002-7850-7827)
- Jie Zeng (ORCID: https://orcid.org/0009-0009-7846-9726)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Beijing Hospital (CN)
- National Center for Clinical Laboratories (CN)
- Dian Diagnostics (China) (CN)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1515/cclm-2025-0186
- Citations
- 1
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Science and Technology Major Project