Impact of surgery and radiation on radicular pain and myotomic weakness in patients with metastatic spine disease
The magnitude of pain improvement for patients with radicular pain following surgery and radiotherapy for metastatic spine disease is higher than for patients with axial pain alone. Surgery is associated with a larger improvement in radicular pain than radiotherapy alone. These results will allow clinicians to tailor treatment options for patients with metastatic spine disease.
Authors
- Arthur R. Bartolozzi (ORCID: https://orcid.org/0000-0001-9391-0502)
- Arjun Sahgal (ORCID: https://orcid.org/0000-0001-7991-8970)
- Michelle J. Clarke (ORCID: https://orcid.org/0000-0003-0358-5633)
- Michael H. Weber (ORCID: https://orcid.org/0000-0002-3176-8165)
- Daniel M. Sciubba (ORCID: https://orcid.org/0000-0001-7604-434X)
- Áron Lazáry (ORCID: https://orcid.org/0000-0002-0157-719X)
- Michael George Fehlings (ORCID: https://orcid.org/0000-0002-5722-6364)
- Ilya Laufer (ORCID: https://orcid.org/0000-0003-0092-5030)
- Laurence D. Rhines (ORCID: https://orcid.org/0000-0002-8474-1521)
- Nicolas Dea
- Charles G. Fisher (ORCID: https://orcid.org/0000-0003-0374-2854)
- Ori Barzilai (ORCID: https://orcid.org/0000-0002-4037-8716)
- Stefano Boriani (ORCID: https://orcid.org/0000-0002-8426-9108)
- Chetan Bettegowda (ORCID: https://orcid.org/0000-0001-9991-7123)
- Ziya L. Gokaslan (ORCID: https://orcid.org/0000-0003-3187-5697)
- James M. Schuster (ORCID: https://orcid.org/0000-0003-3983-5219)
- Mark H. Bilsky (ORCID: https://orcid.org/0000-0001-6091-0709)
- Paul M. Arnold (ORCID: https://orcid.org/0000-0002-4622-7695)
Institutions
- Northwell Health (US)
- Sunnybrook Health Science Centre (CA)
- University Health Network (CA)
- Mayo Clinic (US)
- Memorial Sloan Kettering Cancer Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- University of British Columbia (CA)
- Johns Hopkins University (US)
- University of Illinois Urbana-Champaign (US)
- University of Toronto (CA)
- Brown University (US)
- Toronto Western Hospital (CA)
- Hospital of the University of Pennsylvania (US)
- Rhode Island Hospital (US)
- North Shore University Hospital (US)
- Long Island Jewish Medical Center (US)
- Miriam Hospital (US)
- McGill University Health Centre (CA)
- Presbyterian Hospital (US)
- National Center for Spinal Disorders (HU)
- Istituto Ortopedico Rizzoli (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Neurosurgical FOCUS
- Published
- 2025-05-01
- DOI
- https://doi.org/10.3171/2025.2.focus24915
- Citations
- 1
- Primary Topic
- Management of metastatic bone disease
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- AstraZeneca
- Memorial Sloan-Kettering Cancer Center
- Stryker
- Seagen
- AO Foundation
- Servier