Tensile Strength, Cellular Content and Degradation properties in three generations of concentrated growth factors
The modification of CGF with albumin and silver nanoparticles enhanced degradation resistance, although it did not reach the tensile strength and cellular content of unmodified CGF. Clinically, Alb-CGF and Alb-CGF-SNP serve as effective barrier membranes due to their prolonged stability, while CGF remains advantageous where high mechanical strength is required. Despite lower elasticity limiting suturing, their plasticity supports use as fillers or for tissue phenotype modification in regenerative applications.
Authors
- Mohamed Hassan Elnaem (ORCID: https://orcid.org/0000-0003-0873-6541)
- Malik Hudieb (ORCID: https://orcid.org/0000-0002-1764-2005)
- Jeremy Hamilton (ORCID: https://orcid.org/0000-0002-4500-4625)
- Deborah Lowry (ORCID: https://orcid.org/0000-0003-3919-7456)
- Paul A. McCarron (ORCID: https://orcid.org/0000-0002-2292-9887)
- Ziad Al‐Ani
- Akram Alshirah (ORCID: https://orcid.org/0000-0002-5401-9124)
Institutions
- Tokyo Medical and Dental University (JP)
- University of Ulster (GB)
- Ruchill Hospital (GB)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1186/s12903-025-05825-6
- Citations
- 3
- Primary Topic
- Periodontal Regeneration and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.51
Funders
- Ulster University