Ultrasound and gene-guided microwave ablation vs. surgery for low-risk papillary thyroid carcinoma: a prospective observational cohort study
For patients with low-risk genetic mutations, ablation provides comparable efficacy and disease free survival to surgery, with significant benefits in safety, recovery, and overall cost. Guided by US and next-generation sequencing, precise patient selection enhances the potential of ablation as a promising, minimally invasive alternative to surgery in the management of low-risk PTC .
Authors
- Qingqing Tang (ORCID: https://orcid.org/0000-0002-5177-5573)
- Yisikandaer Yalikun (ORCID: https://orcid.org/0009-0001-3788-2743)
- Yuxin Shen (ORCID: https://orcid.org/0000-0002-6026-2032)
- Yue Zhu (ORCID: https://orcid.org/0000-0003-2870-1397)
- Yunfang Yu (ORCID: https://orcid.org/0000-0001-7475-1796)
- Miaoyun Long (ORCID: https://orcid.org/0009-0000-6896-7785)
- Tian Tian (ORCID: https://orcid.org/0000-0001-6317-943X)
- Qiyun Ou
- Yujie Tan (ORCID: https://orcid.org/0000-0002-2169-2793)
Institutions
- Sun Yat-sen University (CN)
- Jinan University (CN)
- University of Macau (MO)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
- Sun Yat-sen Memorial Hospital (CN)
- First Affiliated Hospital of Jinan University (CN)
Publication Details
- Journal
- Precision Clinical Medicine
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1093/pcmedi/pbaf009
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Sun Yat-sen University
- Basic and Applied Basic Research Foundation of Guangdong Province