High measured GFR as a predictor of all-cause mortality and cardiovascular disease in a prospective non-diabetic population cohort

A high mGFR or eGFRcys is not associated with an increased risk of CVD or all-cause mortality in the general non-diabetic population with normal urine ACR. Previous findings of an association with high eGFRcrea were most likely caused by non-GFR confounders. In persons with high-normal ACR, high mGFR or eGFRcys is associated with an increased risk of CVD.

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Publication Details

Journal
Nephrology Dialysis Transplantation
Published
2025-04-29
DOI
https://doi.org/10.1093/ndt/gfaf079
Citations
2
Primary Topic
Chronic Kidney Disease and Diabetes
Type
article
Field-Weighted Citation Impact
2.86

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article

High measured GFR as a predictor of all-cause mortality and cardiovascular disease in a prospective non-diabetic population cohort

Jon Viljar Norvik, Matteo Fasiolo, Toralf Melsom, Vidar T.N. Stefansson et al.
2 citations
Nephrology Dialysis Transplantation
Chronic Kidney Disease and Diabetes
2.86
article

High measured GFR as a predictor of all-cause mortality and cardiovascular disease in a prospective non-diabetic population cohort

Jon Viljar Norvik, Matteo Fasiolo, Toralf Melsom, Vidar T.N. Stefansson, Trond Jenssen, Ulla Dorte Mathisen, Björn O. Eriksen, Jørgen Schei
article en
2 citations

Abstract

A high mGFR or eGFRcys is not associated with an increased risk of CVD or all-cause mortality in the general non-diabetic population with normal urine ACR. Previous findings of an association with high eGFRcrea were most likely caused by non-GFR confounders. In persons with high-normal ACR, high mGFR or eGFRcys is associated with an increased risk of CVD.

Nephrology Dialysis TransplantationVol. 40(11)
Oslo University Hospital (NO), University Hospital of North Norway (NO), University of Oslo (NO), University of Bristol (GB), UiT The Arctic University of Norway (NO)
Universitetet i Tromsø
Good health and well-being
Openalex Percentile: Top 10%
Chronic Kidney Disease and Diabetes
2.86
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High measured GFR as a predictor of all-cause mortality and cardiovascular disease in a prospective non-diabetic population cohort — Jon Viljar Norvik, Matteo Fasiolo, et al. · Nephrology Dialysis Transplantation (2025) | TGRS Research Map | TGRS