Comparison of Platelet Indices in Women with Preeclampsia Versus Women Without Preeclampsia

Objective: To determine difference in platelet indices among pregnant ladies with preeclampsia as compared to those pregnant ladies without preeclampsia using platelet indices as biomarkers for predicting the disease and its severity. Study Design: Comparative cross sectional study. Place and Duration of Study: Department of Pathology and The Department of Obstetrics and Gynecology, Rashid Latif Khan University Medical and Dental College Lahore, Pakistan from Jan-Jun 2023. Methodology: Pregnant women falling on inclusion criteria were included in this study using nonprobability consecutive sampling technique. Complete blood count with platelet indices, and serum sugar were determined. Study sample was divided into two groups. Patients without preeclampsia were placed in Group-A (n=60), those with preeclampsia were put into Group-B (n=60). Platelet indices were compared between two groups including platelet count, mean platelet volume (MPV), Plateletcrit and platelet distribution width (PDW). Results: Total 120 cases with preeclampsia were studied. Mean hemoglobin level was 13.24±2.10 g/dl in Group-A, 12.73±1.80 g/dl in Group-B. Mean platelet count was 277±88 x109/L in Group-A, 301±84 x109/L in Group-B. MPV was 12.07±1.03fL in Group-A and 11.21±1.31fL in Group-B. Conclusion: Platelet indices are altered among the patients with preeclampsia as compared to normal individuals, hence indicating as important biomarker for assessing the disease.