Analysis of Adverse Reactions Caused by Antibiotics and Rational Drug Use in Clinical Practice

Objective: To explore the adverse reactions associated with antibiotics and analyze strategies for their rational use. Methods: A retrospective analysis was conducted on 60 patients who experienced adverse reactions to antibiotics between August 2021 and August 2023. The types of antibiotics that caused adverse reactions were analyzed, and the symptoms of adverse reactions and measures for rational use of antibiotics were summarized. Results: Among the analyzed cases of adverse reactions to antibiotics, the highest rate was observed in patients aged 61–75 years, accounting for 38.33%, followed by patients aged 51–60 years, accounting for 20.00%. In terms of the types of antibiotics that caused adverse reactions, cephalosporins were the most common, accounting for 40.00%, followed by penicillins, accounting for 18.33%. Analysis of the systems involved in adverse reactions showed that skin and appendage disorders were the most common, accounting for 36.67%, followed by the digestive system, accounting for 28.33%. Conclusion: Irrational use of antibiotics can lead to adverse drug reactions. Therefore, it is necessary to analyze strategies for the rational use of antibiotics to reduce adverse drug reactions and ensure the safety of antibiotic use.