Correlation Analysis Between 3D and Plane DAT Binding Parameters of 11C-CFT PET/CT and the Clinical Characteristics of Patients with Parkinson’s Disease
Quantitative parameters based on plane and 3D images of <sup>11</sup>C-CFT PET/CT showed good consistency. Moreover, 3D parameters in the neostriatum had a stronger correlation with activities of daily living, UPDRS motor scores, disease severity and duration, and cognition compared with plane parameters in PD patients.
Authors
- Jing Gan (ORCID: https://orcid.org/0000-0001-5255-6324)
- Chuantao Zuo (ORCID: https://orcid.org/0000-0002-8856-7217)
- Sheng Liang (ORCID: https://orcid.org/0000-0002-6809-5865)
- Lin Ding (ORCID: https://orcid.org/0000-0002-0265-9613)
- Ping Wu (ORCID: https://orcid.org/0000-0002-2758-1218)
- Zhenguo Liu (ORCID: https://orcid.org/0000-0003-1743-2937)
- Hui Wang (ORCID: https://orcid.org/0000-0001-5109-8691)
- Xiaodong Wu (ORCID: https://orcid.org/0009-0009-0863-5733)
- Yafu Yin (ORCID: https://orcid.org/0000-0002-4818-6655)
- Ziyuan Li
- Yufei Ma
- Feng Wei
Institutions
- Shanghai Jiao Tong University (CN)
- Fudan University (CN)
- XinHua Hospital (CN)
- Shandong Tumor Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Journal of Integrative Neuroscience
- Published
- 2025-04-25
- DOI
- https://doi.org/10.31083/jin24440
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China
- Science and Technology Commission of Shanghai Municipality