FCGR1A Alleviates Ischemic Stroke-induced Injury by Promoting Anti-Inflammatory Microglial Polarization via the AMPK–mTOR Signaling Pathway
<i>FCGR1A</i> modulates microglial polarization by affecting the AMPK-mTOR signaling pathway in ischemic conditions. Targeting <i>FCGR1A</i> and related pathways could offer new therapeutic strategies to lessen inflammation and facilitate the healing process after an ischemic stroke.
Authors
- Meng Liu (ORCID: https://orcid.org/0000-0002-2445-2525)
- Yufeng Yan
- D Chen
- Xiang‐Bing Fan
- Yuqi Wang
- Hui-Bin Yao
- Haihan Song (ORCID: https://orcid.org/0009-0006-7753-8628)
- Qing Zhang (ORCID: https://orcid.org/0009-0009-5817-8243)
- H. Li
- Zhihui Huang
Institutions
- Jiangsu University (CN)
- Jinshan Hospital of Fudan University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-04-29
- DOI
- https://doi.org/10.31083/fbl26614
- Citations
- 1
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- Fudan University