Aerobic Exercise Ameliorates Alzheimer’s Disease-Like Pathology by Regulating Hepatic Phagocytosis of Aβ
Our findings indicated that AIT and ACT can improve cognitive deficits in APP/PS1 mice, potentially by increasing the hepatic phagocytic capacity of Aβ. Hepatic clearance of Aβ may serve as a supplementary mechanism by which aerobic exercise can improve AD.
Authors
- Shan Wang (ORCID: https://orcid.org/0000-0002-1124-8402)
- Naichun Ji (ORCID: https://orcid.org/0009-0004-4974-9116)
- Xingchun Gou (ORCID: https://orcid.org/0000-0001-6732-3101)
- Qing Wang
- F. B. Hu
Institutions
- Xi'an Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-04-22
- DOI
- https://doi.org/10.31083/fbl36597
- Citations
- 2
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.33
Funders
- National Natural Science Foundation of China