Co-Highly Expressed SLC17A9 and KCNH1 as Potential Prognostic Biomarkers and Therapeutic Targets in Clear Cell Renal Cell Carcinoma
SLC17A9 and KCNH1 serve as critical prognostic biomarkers in ccRCC, with SLC17A9 driving tumor progression through KCNH1 regulation. Their upregulated expression predicts poor clinical outcomes, while reduced levels correlate with improved survival, highlighting their dual role as therapeutic targets.
Authors
- Jun Xiao (ORCID: https://orcid.org/0000-0001-9012-1110)
- Xiangyu Mu (ORCID: https://orcid.org/0000-0002-5727-5035)
- Bing Zhong (ORCID: https://orcid.org/0000-0001-9986-0462)
- Xuechun Hu (ORCID: https://orcid.org/0000-0003-0533-7369)
- Zhiwang Tang (ORCID: https://orcid.org/0000-0001-9603-603X)
- Deyun Shen
- Yixun Liu
- Zongpan Ke (ORCID: https://orcid.org/0009-0009-4562-5833)
- Zexuan Li (ORCID: https://orcid.org/0009-0004-7067-6572)
- Ping Xiang
- Ruoyun Tan (ORCID: https://orcid.org/0009-0001-5052-5011)
- Yawei Shu (ORCID: https://orcid.org/0009-0004-9592-5184)
Institutions
- University of Science and Technology of China (CN)
- Huaian First People’s Hospital (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-04-18
- DOI
- https://doi.org/10.31083/fbl38061
- Primary Topic
- Renal and related cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China