Periodontal Disease and Age-Related Maculopathy: A Case Report

Age-related macular degeneration (AMD) is a leading cause of significant vision impairment in individuals aged 50 and older, primarily impacting central vision. This study seeks to investigate potential associations between periodontal disease and age-related maculopathy in the analyzed clinical case. A male subject of 66 years old, with age-related degenerative maculopathy and severe periodontal disease, was evaluated and treated. After an initial phase of non-surgical causal periodontal therapy, the periodontal indices were re-evaluated. In addition, the extraction of hopeless teeth replaced by dental implants was performed. A retinal topography was used to assess possible regression of the pathology, and proper anti-VEGF therapy was administered. The results showed a regression of periodontal disease and an improvement of the degenerative maculopathy. These preliminary results, even if encouraging, should be supported by larger prospective trials.

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Publication Details

Journal
Clinical Medicine Insights Case Reports
Published
2025-04-29
DOI
https://doi.org/10.1177/11795476251333251
Primary Topic
Retinal Diseases and Treatments
Type
article
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article

Periodontal Disease and Age-Related Maculopathy: A Case Report

Sara Cecilia Soto‐De León, Artak G. Heboyan, Marco Cicciù, Gabriele Cervino et al.
Clinical Medicine Insights Case Reports
Retinal Diseases and Treatments
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Periodontal Disease and Age-Related Maculopathy: A Case Report

Sara Cecilia Soto‐De León, Artak G. Heboyan, Marco Cicciù, Gabriele Cervino, Silvio Mario Meloni, Marco Tallarico, Luca Fiorillo, Francesco Mattia Ceruso, Francesco Pernice
article en

Abstract

Age-related macular degeneration (AMD) is a leading cause of significant vision impairment in individuals aged 50 and older, primarily impacting central vision. This study seeks to investigate potential associations between periodontal disease and age-related maculopathy in the analyzed clinical case. A male subject of 66 years old, with age-related degenerative maculopathy and severe periodontal disease, was evaluated and treated. After an initial phase of non-surgical causal periodontal therapy, the periodontal indices were re-evaluated. In addition, the extraction of hopeless teeth replaced by dental implants was performed. A retinal topography was used to assess possible regression of the pathology, and proper anti-VEGF therapy was administered. The results showed a regression of periodontal disease and an improvement of the degenerative maculopathy. These preliminary results, even if encouraging, should be supported by larger prospective trials.

Clinical Medicine Insights Case ReportsVol. 18
University of Messina (IT), University of Sassari (IT), University of Campania "Luigi Vanvitelli" (IT), University of Catania (IT), Dr. D.Y. Patil Vidyapeeth, Pune (IN), Dr D Y Patil Dental College & Hospital (IN), Ospedale San Pietro Fatebenefratelli (IT), Yerevan State Medical University (AM)
Good health and well-being
Openalex Percentile: Top 85%
Retinal Diseases and Treatments
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