The Effect and Safety of Dexmedetomidine Administration on Mother and Foetus/Neonates During General Anaesthesia in Caesarean Section: A Randomised Controlled Trial
Intravenous 0.4 or 0.6 µg/kg doses of dexmedetomidine with propofol for general anesthesia in CS is beneficial for inhibiting the maternal stress response induced by intubation/skin incision and delivery without significant adverse effects on fetuses or neonates. Our findings suggest that dexmedetomidine is safe for mothers, fetuses, and neonates in obstetric general anesthesia.
Authors
- Fengxia Duan
- M. Zhang
- Qi Zhao (ORCID: https://orcid.org/0000-0003-0140-3920)
- Qian Li (ORCID: https://orcid.org/0000-0001-8827-939X)
- Yan Liu (ORCID: https://orcid.org/0000-0002-9123-4974)
- Li Zhang (ORCID: https://orcid.org/0000-0002-3617-2627)
- Zhuangzhuang Wang (ORCID: https://orcid.org/0000-0003-4701-7574)
- Zhiqiang Yu (ORCID: https://orcid.org/0000-0002-2869-2796)
- Yan Dong
Institutions
- Nankai University (CN)
- Tianjin Central Hospital of Gynecology Obstetrics (CN)
Publication Details
- Journal
- Journal of Investigative Surgery
- Published
- 2025-04-30
- DOI
- https://doi.org/10.1080/08941939.2025.2495089
- Citations
- 3
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 6.57