Microbiome-Mediated Disease Suppression: A Promising Avenue for Phytophthora Management in Commercial Crops Using Phytochemicals Obtained from Medicinal Plants

Microbiome-mediated disease suppression and the use of phytochemicals from medicinal plants present promising strategies for managing phytophthora infections in commercial crops. This study explores the synergistic effects of combining microbiome-based approaches with phytochemicals to enhance disease resistance and broaden the applicability of these innovative strategies. The development of bioformulations integrating beneficial microbes with plant-derived compounds for targeted delivery offers optimized interaction and stability, thereby improving disease control. Advanced technologies such as metagenomics and metabolomics play a crucial role in understanding microbial communities and developing targeted strategies to promote the growth and activity of beneficial microbes in the field. Addressing key research gaps, including the mechanisms of plant-derived compounds and beneficial microbes in combating Phytophthora, and the variability of microbiomes across different environments, underscores the need for tailored approaches for disease management. Optimizing application methods for microbiome and phytochemical treatments in various agricultural settings is essential to enhance efficacy and sustainability, considering environmental factors that influence microbial and phytochemical activity. This comprehensive review highlights the potential of microbiome-mediated disease suppression in commercial crops and underscores the importance of further research to realize the full benefits of these innovative approaches.