Application of metagenomic next-generation sequencing in the diagnosis and treatment of acute pneumonia caused by Tropheryma whipplei

The mNGS examination of bronchoalveolar lavage fluid can significantly improve the early diagnosis of acute pneumonia caused by Tropheryma whipplei. The treatment involving imipenem-cilastatin combined with SMZ-TMP, followed by oral SMZ-TMP for three months, is effective.

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Publication Details

Journal
BMC Pulmonary Medicine
Published
2025-04-30
DOI
https://doi.org/10.1186/s12890-025-03657-2
Citations
3
Primary Topic
Whipple's Disease and Interleukins
Type
article
Field-Weighted Citation Impact
4.41
Controls
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article

Application of metagenomic next-generation sequencing in the diagnosis and treatment of acute pneumonia caused by Tropheryma whipplei

Yanhong Huo, Dai-yuan Ma, Chao Wu
3 citations
BMC Pulmonary Medicine
Whipple's Disease and Interleukins
4.41
article

Application of metagenomic next-generation sequencing in the diagnosis and treatment of acute pneumonia caused by Tropheryma whipplei

Yanhong Huo, Dai-yuan Ma, Chao Wu
article en
3 citations

Abstract

The mNGS examination of bronchoalveolar lavage fluid can significantly improve the early diagnosis of acute pneumonia caused by Tropheryma whipplei. The treatment involving imipenem-cilastatin combined with SMZ-TMP, followed by oral SMZ-TMP for three months, is effective.

BMC Pulmonary MedicineVol. 25(1)
Jiangsu Province Hospital (CN)
Zero hunger
Openalex Percentile: Top 6%
Whipple's Disease and Interleukins
4.41
DOIOpen Access PDFOpenAlex
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Application of metagenomic next-generation sequencing in the diagnosis and treatment of acute pneumonia caused by Tropheryma whipplei — Yanhong Huo, Dai-yuan Ma, et al. · BMC Pulmonary Medicine (2025) | TGRS Research Map | TGRS