Development and validation of a prediction model for early recurrence in upper tract urothelial carcinoma treated with radical nephroureterectomy

This study identified the optimal time point for early recurrence and its associated risk factors. A prediction model for early recurrence was developed based on these factors and validated externally, demonstrating good generalizability. This clinical tool can facilitate early identification of high-risk patients, enabling targeted surveillance and timely intervention. Future studies should explore effective treatment strategies for preventing early recurrence.

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Publication Details

Journal
BMC Cancer
Published
2025-04-30
DOI
https://doi.org/10.1186/s12885-025-14180-2
Citations
2
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
Field-Weighted Citation Impact
4.01

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article

Development and validation of a prediction model for early recurrence in upper tract urothelial carcinoma treated with radical nephroureterectomy

Shian‐Shiang Wang, Marcin Chłosta, Chung‐Hsin Chen, Pai-Yu Cheng et al.
2 citations
BMC Cancer
Bladder and Urothelial Cancer Treatments
4.01
article

Development and validation of a prediction model for early recurrence in upper tract urothelial carcinoma treated with radical nephroureterectomy

Shian‐Shiang Wang, Marcin Chłosta, Chung‐Hsin Chen, Pai-Yu Cheng, Yu‐Khun Lee, Hao‐Lun Luo, See‐Tong Pang, YC Hsieh, Ekaterina Laukhtina, Tamás Fazekas, Chuan-Shu Chen, Po‐Hung Lin, Wei‐Yu Lin, Marco Moschini, Ian-Seng Cheong, Hsi‐Chin Wu, Han‐Yu Weng, Wei-Chieh Chen, Jeremy Yuen‐Chun Teoh, Marcelo Chen, Steven K. Huang, Pi-Che Chen, Shahrokh François Shariat, Jian‐Hua Hong, Ta‐Yao Tai, Jen‐Shu Tseng, Chao-Hsiang Chang, Hung‐Jen Wang, I‐Hsuan Chen, Wen-Jeng Wu, Richard C. Wu, Yi-Ju Chou, Francesco Soria, Yao-Chou Tsai, Chia-Cheng Yu, Chia-Chang Wu, Yung-Tai Chen, Chi-Wen Lo, Yuan‐Hong Jiang, Thomas Y. Hsueh, Ching‐Chia Li, Chung‐You Tsai
article en
2 citations

Abstract

This study identified the optimal time point for early recurrence and its associated risk factors. A prediction model for early recurrence was developed based on these factors and validated externally, demonstrating good generalizability. This clinical tool can facilitate early identification of high-risk patients, enabling targeted surveillance and timely intervention. Future studies should explore effective treatment strategies for preventing early recurrence.

BMC CancerVol. 25(1)
Semmelweis University (HU), Al-Ahliyya Amman University (JO), Jagiellonian University (PL), National Taichung University of Science and Technology (TW), Chang Gung University of Science and Technology (TW), National Yang Ming Chiao Tung University (TW), Kaohsiung Medical University (TW), Vita-Salute San Raffaele University (IT), National Taiwan University (TW), Chang Gung University (TW), Chinese University of Hong Kong (HK), China Medical University (TW), Tzu Chi University (TW), National Chi Nan University (TW), Cornell University (US), Tzu Chi Foundation (TW), Taipei Medical University Hospital (TW), Kaohsiung Medical University Chung-Ho Memorial Hospital (TW), Mackay Memorial Hospital (TW), Chang Gung Memorial Hospital (TW), Mackay Medical University (TW), E-Da Hospital (TW), Taichung Veterans General Hospital (TW), Comprehensive Cancer Center Vienna (AT), Kaohsiung Chang Gung Memorial Hospital (TW), Taipei Tzu Chi Hospital (TW), Far Eastern Memorial Hospital (TW), Chia-Yi Christian Hospital (TW), China Medical University Beigang Hospital (TW), Taipei City Hospital (TW), Hualien Tzu Chi Medical Center (TW), China Medical University Hospital (TW), Mackay Junior College of Medicine, Nursing and Management (TW), Taipei Hospital (TW), National Taiwan University Hospital (TW), Chi Mei Medical Center (TW), Kaohsiung Veterans General Hospital (TW), Chiayi Chang Gung Memorial Hospital (TW), Taipei Medical University-Shuang Ho Hospital (TW), National Cheng Kung University Hospital (TW), Karl Landsteiner Society (AT), Taipei Medical University (TW), Medical University of Vienna (AT), Chang Jung Christian University (TW), The University of Texas Southwestern Medical Center (US), Chung Shan Medical University (TW), National Cheng Kung University (TW), I-Shou University (TW), Yuan Ze University (TW)
Buddhist Tzu Chi Medical Foundation, Taipei Tzu Chi Hospital
Peace, Justice and strong institutions
Openalex Percentile: Top 8%
Bladder and Urothelial Cancer Treatments
4.01
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