Discovering a Case of Lisinopril-Induced Necrotizing Pancreatitis

Acute pancreatitis (AP) is one of the most common gastrointestinal diagnoses for inpatient admissions, with medications being a rare inciting agent. Our case highlights a 55-year-old male patient who was admitted for recurring epigastric pain and elevated lipase levels, with imaging showing AP with necrosis. After common etiologies for AP, including gallstones and alcohol, were ruled out, medication reconciliation showed that lisinopril was prescribed concurrently with the onset of AP episodes. Once lisinopril was discontinued, the patient's symptoms resolved. This case aims to make healthcare professionals aware of AP as a side effect of lisinopril.