Analysis of the effect of fecal SDC2, ADHFE1 and PPP2R5C gene methylation test for screening colorectal cancer in the Otog Front Banner
Fecal SDC2, ADHFE1, and PPP2R5C gene methylation detection methods can serve as primary screening tools, supplemented by colonoscopy, to effectively detect colorectal cancer and precancerous lesions. This strategy may prove to be an effective approach for conducting large-scale colorectal cancer screening in average-risk populations.
Authors
- Mei Lan (ORCID: https://orcid.org/0000-0002-5591-2678)
- Runxiang Chen
- Shiiu Chen
- Shimei Huang
- Feihu Bai (ORCID: https://orcid.org/0000-0002-1560-6131)
- Daya Zhang (ORCID: https://orcid.org/0000-0001-6133-8919)
- Da Li (ORCID: https://orcid.org/0009-0002-7896-024X)
- Jinrun Chen (ORCID: https://orcid.org/0009-0005-2145-8015)
- Xiaodong Zhang (ORCID: https://orcid.org/0000-0001-5039-6363)
- Fan Zeng (ORCID: https://orcid.org/0000-0002-5461-9912)
- Chen Chen (ORCID: https://orcid.org/0000-0003-2104-534X)
- Xuli Zhu
Institutions
- Jiujiang University (CN)
- Inner Mongolia People's Hospital (CN)
- Hainan Medical College Hospital (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-04-30
- DOI
- https://doi.org/10.1186/s12876-025-03737-x
- Primary Topic
- Colorectal Cancer Screening and Detection
- Type
- article
- Field-Weighted Citation Impact
- 0.00