Vancomycin individual dosing regimens via Bayesian simulation: a 5-year retrospective study on preterm and term neonates

Vancomycin overdosage should be avoided in very young premature babies (PMA = 25 weeks). Optimization of efficacy while minimizing toxicity of vancomycin in preterm and term neonates is needed, especially guided by personalized body weight, postmenstrual age, and renal function.

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Publication Details

Journal
Personalized Medicine
Published
2025-04-30
DOI
https://doi.org/10.1080/17410541.2025.2499442
Primary Topic
Antimicrobial Resistance in Staphylococcus
Type
article
Field-Weighted Citation Impact
0.00
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article

Vancomycin individual dosing regimens via Bayesian simulation: a 5-year retrospective study on preterm and term neonates

Minzhen Han, Heng Liang, Alexander Chao, Lu Tan et al.
Personalized Medicine
Antimicrobial Resistance in Staphylococcus
article

Vancomycin individual dosing regimens via Bayesian simulation: a 5-year retrospective study on preterm and term neonates

Minzhen Han, Heng Liang, Alexander Chao, Lu Tan, Qian Liu, Yanping Guan
article en

Abstract

Vancomycin overdosage should be avoided in very young premature babies (PMA = 25 weeks). Optimization of efficacy while minimizing toxicity of vancomycin in preterm and term neonates is needed, especially guided by personalized body weight, postmenstrual age, and renal function.

Personalized MedicineVol. 22(3)
Third Affiliated Hospital of Southern Medical University (CN), Affiliated Hospital of Guizhou Medical University (CN)
Zero hunger
Openalex Percentile: Top 88%
Antimicrobial Resistance in Staphylococcus
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