The development of a multiplex recombinase polymerase amplification reaction to detect the most common causative agents of eumycetoma
We developed a field-friendly multiplex RPA, that successfully detects fungal DNA and discriminates between M. mycetomatis and F. senegalensis. This tool holds promise for enhancing diagnostic capabilities in eumycetoma endemic regions, paving the way for improved patient management and treatment outcomes.
Authors
- Maria Faye (ORCID: https://orcid.org/0000-0001-9838-5364)
- Kimberly Eadie (ORCID: https://orcid.org/0009-0001-0436-7008)
- Ahmed Hassan Fahal (ORCID: https://orcid.org/0000-0003-4922-7321)
- Mickey Konings (ORCID: https://orcid.org/0000-0003-3983-4304)
- Doudou Sow (ORCID: https://orcid.org/0000-0002-0560-2372)
- Emmanuel Edwar Siddig (ORCID: https://orcid.org/0000-0001-6314-7374)
- Annelies Verbon (ORCID: https://orcid.org/0000-0003-2242-8342)
- Carole Pab Minlekib
- Wendy W. J. van de Sande (ORCID: https://orcid.org/0000-0002-8652-8783)
Institutions
- Université Gaston Berger (SN)
- University of Medical Sciences and Technology (SD)
- University of Khartoum (SD)
- University of Applied Sciences Utrecht (NL)
- Utrecht University (NL)
- Erasmus MC (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- European Journal of Clinical Microbiology & Infectious Diseases
- Published
- 2025-04-30
- DOI
- https://doi.org/10.1007/s10096-025-05134-4
- Citations
- 1
- Primary Topic
- Actinomycetales infections and treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.04