A rare cause of methemoglobinemia; food protein-induced enterocolitis syndrome

Food protein-induced enterocolitis syndrome, an uncommon non-immunoglobuline-E mediated food hypersensitivity, is characterized by profuse vomiting, diarrhea and acute dehydration. There are no specific laboratory findings, however leukocytosis, metabolic acidosis and rarely methemoglobinemia may be observed. The primary treatment involves elimination of the food that causes the allergic reaction. Here we report the case of a 45-day-old female infant diagnosed acute food protein-induced enterocolitis syndrome co-existing with methemoglobinemia.