Stroke and Thrombotic Events Associated With Concomitant Use of Oral Anticoagulants and Antiepileptic Drugs in the United States and Japan
We observed an increase in the odds of reporting anticoagulation treatment failure among patients treated with DOACs and concomitant first-generation AEDs compared to those treated with control AEDs in the FAERS database. Care should be taken when administering dabigatran, apixaban, and rivaroxaban.
Authors
- Ryo Yonezawa (ORCID: https://orcid.org/0000-0002-2970-0217)
- Tomiko Sunaga (ORCID: https://orcid.org/0000-0002-1316-5192)
Institutions
- Hoshi University (JP)
- SHOWA Medical University Hospital (JP)
Publication Details
- Journal
- Cureus
- Published
- 2025-04-30
- DOI
- https://doi.org/10.7759/cureus.83268
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00