GLUT5 armouring enhances adoptive T-cell therapy anti-tumour activity under glucose-limiting conditions
This straightforward modification is compatible with current clinical approaches and may improve the efficacy of T-cell therapies for solid tumours.
Authors
- Sophie Papa (ORCID: https://orcid.org/0000-0002-9063-7675)
- Robert L. Page (ORCID: https://orcid.org/0000-0002-9288-694X)
- Daniel Larcombe-Young (ORCID: https://orcid.org/0000-0002-3579-8695)
- Eva Bugallo-Blanco (ORCID: https://orcid.org/0000-0002-4350-0625)
- Esperanza Perucha (ORCID: https://orcid.org/0000-0002-7802-0875)
- Olivier Martínez (ORCID: https://orcid.org/0000-0002-3950-5458)
Institutions
- King's College London (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
Publication Details
- Journal
- Immunotherapy Advances
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1093/immadv/ltaf018
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research
- King's College London