[Catalpol reduces liver toxicity of triptolide in mice by inhibiting hepatocyte ferroptosis through the SLC7A11/GPX4 pathway: testing the <i>Fuzheng Zhidu</i> theory for detoxification].
The combined use of catalpol can reduce the hepatotoxicity of triptolide in mice by inhibiting excessive hepatocyte ferroptosis through the SLC7A11/GPX4 pathway.
Authors
- Yuanyuan Lou
- Lingling Huang (ORCID: https://orcid.org/0000-0002-7790-2788)
- Linluo Zhang
- Changqing Li (ORCID: https://orcid.org/0000-0003-2994-4315)
- Xueping Zhou (ORCID: https://orcid.org/0000-0001-7170-0192)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Xuzhou Medical College (CN)
- Huaian First People’s Hospital (CN)
- Second People’s Hospital of Huai’an (CN)
- Jiangsu Food and Pharmaceutical Science College (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.04.16
- Primary Topic
- Natural Compounds in Disease Treatment
- Type
- article