[Activation of astrocytes in the dorsomedial hypothalamus accelerates sevoflurane anesthesia emergence in mice].
Optogenetic activation of DMH astrocytes facilitates sevoflurane anesthesia emergence but does not significantly influence anesthesia induction. These findings offer new insights into the mechanisms underlying anesthesia emergence and may provide a potential target for accelerating postoperative recovery and managing anesthesia-related complications.
Authors
- Xinyu Hao (ORCID: https://orcid.org/0000-0002-1764-0499)
- Shuting Guo (ORCID: https://orcid.org/0009-0003-9929-1329)
- Zhuoning Zhang
- Yanxiang Li (ORCID: https://orcid.org/0000-0002-5248-6757)
- Yongxin Guo
- Fuyang Cao (ORCID: https://orcid.org/0000-0002-3746-8489)
- Tong Li (ORCID: https://orcid.org/0000-0001-5729-1839)
- Zhikang Zhou (ORCID: https://orcid.org/0000-0003-1280-1852)
- Jiangbei Cao (ORCID: https://orcid.org/0000-0003-1218-4639)
Institutions
- Chinese PLA General Hospital (CN)
- United States Army (US)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.04.10
- Primary Topic
- Anesthesia and Neurotoxicity Research
- Type
- article