[High expression of DTX2 promotes proliferation, invasion and epithelial-mesenchymal transition of oxaliplatin-resistant colorectal cancer cells].
High expression of DTX2 promotes proliferation, migration, invasion and EMT of CRC/OXA cells through the Notch2 signaling pathway, suggesting the potential of DTX2 as a target to improve the efficacy of oxaliplatin.
Authors
- Zhennan Ma (ORCID: https://orcid.org/0009-0006-0619-4354)
- Xuefeng Zhao (ORCID: https://orcid.org/0000-0002-1704-4021)
- Xiaowei Zhang (ORCID: https://orcid.org/0000-0002-9903-6980)
- Fuquan Liu (ORCID: https://orcid.org/0000-0001-8764-6370)
Institutions
- Affiliated Zhongshan Hospital of Dalian University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.04.18
- Primary Topic
- Colorectal Cancer Treatments and Studies
- Type
- article