[Hypertension exacerbates postoperative learning and memory impairment in rats possibly due to UCP2 downregulation-mediated mitochondrial dysfunction].
Hypertension can exacerbate major postoperative learning and memory impairment in rats possibly as a result of UCP2-mediated mitochondrial dysfunction and oxidative stress damage, which further leads to astrocyte overactivation and neuronal damage.
Authors
- Luyu Liu (ORCID: https://orcid.org/0000-0002-6684-5570)
- Qiang Fu (ORCID: https://orcid.org/0000-0002-5191-3315)
- Min Gong (ORCID: https://orcid.org/0000-0002-3749-1419)
- Weixing Zhao (ORCID: https://orcid.org/0000-0001-5326-2977)
- Guosong Liao
Institutions
- Chinese PLA General Hospital (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.04.07
- Primary Topic
- Anesthesia and Neurotoxicity Research
- Type
- article